News

New publication by the Krämer lab on how inhibitors of the tyrosine kinases FMS-like tyrosine kinase-3 and WEE1 induce apoptosis and DNA damage synergistically in acute myeloid leukemia cells

SFB 1361 Project Leader Helle Ulrich awarded an ERC Advanced Grant

New publication by the Stingele lab on genomic barcoding for clonal diversity monitoring and control in cell-based complex antibody production

New publication by the Stingele lab on electro-elution-based purification of covalent DNA-protein cross-links

New joint publication by the Beli, Christmann and Hofmann labs on how the p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence

New joint publication by the Beli and Stingele labs on how decitabine cytotoxicity is promoted by dCMP deaminase DCTD and mitigated by SUMO-dependent E3 ligase TOPORS

New publication by the Cardoso lab on DNA choreography: correlating mobility and organization of DNA across different resolutions from loops to chromosomes

New joint publication by the Beli and Roukos labs on linking CRISPR–Cas9 double-strand break profiles to gene editing precision with BreakTag

New publication from the Roukos lab on high clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue

New publication from the Stingele lab on the quantification of intracellular DNA-protein cross-Links with N7-Methyl-2'-Deoxyguanosine and their contribution to cytotoxicity

New publication from the Stingele lab on the transcription-coupled repair of DNA–protein cross-links depends on CSA and CSB

New publication from the Krämer lab on how pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells