Mainz, Nov. 25, 2022 - The German Research Foundation (DFG) announced the prolongation of the Collaborative Research Centre (CRC) 1361: "Regulation of DNA Repair and Genome Stability" for an…
RESEARCH HIGHLIGHTS
07 November – The research group of Prof. Christof Niehrs at the Institute of Molecular Biology (IMB) has discovered a new chemical modification of mammalian DNA called…
10-11-2022
PARP1 mediates poly-ADP-ribosylation of proteins on chromatin in response to different types of DNA lesions. PARP inhibitors are used for the treatment of BRCA1/2-deficient breast,…
5 September – Ageing is one of the greatest challenges facing our society. Soon, one-third of our population will be over the age of 65 and many of these will suffer from age-related diseases, such…
DNA double-strand breaks (DSBs) threaten genome stability and are linked to tumorigenesis in humans. Repair of DSBs requires the removal of attached proteins and hairpins through a poorly understood…