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306 results:
141. Continued excellence in DNA repair and genome stability research: DFG renews collaborative research centre at Johannes Gutenberg University Mainz  
Mainz, Nov. 25, 2022 - The German Research Foundation (DFG) announced the prolongation of the Collaborative Research Centre (CRC) 1361: "Regulation of DNA Repair and Genome Stability" for an…  
145. Scientists in the Niehrs lab discover a new DNA base modification in mammals  
RESEARCH HIGHLIGHTS 07 November – The research group of Prof. Christof Niehrs at the Institute of Molecular Biology (IMB) has discovered a new chemical modification of mammalian DNA called…  
146. The SFB projects from Petra Beli, Vassilis Roukos and Katja Luck have published a joned paper on "PARP1 proximity proteomics reveals interaction partners at stressed replication forks"  
10-11-2022 PARP1 mediates poly-ADP-ribosylation of proteins on chromatin in response to different types of DNA lesions. PARP inhibitors are used for the treatment of BRCA1/2-deficient breast,…  
148. Public Lecture "The mystery of human ageing: New insights from the biology of ageing" by Prof. Björn Schumacher  
5 September – Ageing is one of the greatest challenges facing our society. Soon, one-third of our population will be over the age of 65 and many of these will suffer from age-related diseases, such…  
150. New publication from the Hopfner lab: "Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50"  
DNA double-strand breaks (DSBs) threaten genome stability and are linked to tumorigenesis in humans. Repair of DSBs requires the removal of attached proteins and hairpins through a poorly understood…  
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