2023
González A and Dikić I (2023) Decoding Golgiphagy: selective recycling under stress. Cell Res, doi: 10.1038/s41422-023-00905-0 Link
Mende H, Khatri A, Lange C, Poveda-Cuevas SA, Tascher G, Covarrubias-Pinto A, Löhr F, Koschade SE, Dikic I, Münch C, Bremm A, Brunetti L, Brandts CH, Uckelmann H, Dötsch V, Rogov V V., Bhaskara RM and Müller S (2023) An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant. Cell Rep, doi: 10.1016/j.celrep.2023.113484 Link
Patil PR, Burroughs AM, Misra M, Cerullo F, Costas-Insua C, Hung H-C, Dikic I, Aravind L and Joazeiro CAP (2023) Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10. Cell Rep, doi: 10.1016/j.celrep.2023.113100 Link
Mello-Vieira J, Bopp T and Dikic I (2023) Ubiquitination and cell-autonomous immunity. Curr Opin Immunol, doi: 10.1016/j.coi.2023.102368 Link
Schierwagen R, Gu W, Brieger A, Brüne B, Ciesek S, Đikić I, Dimmeler S, Geisslinger G, Greten FR, Hermann E, Hildt E, Kempf VAJ, Klein S, Koch I, Mühl H, Müller V, Peiffer K-H, Kestner R-I, Piiper A, Rohde G, Scholich K, Schulz MH, Storf H, Toptan T, Vasa-Nicotera M, Vehreschild MJGT, Weigert A, Wild PJ, Zeuzem S, Engelmann C, Schaefer L, Welsch C and Trebicka J (2023) Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure. Am J Physiol Physiol, doi: 10.1152/ajpcell.00101.2023 Link
Pérez Berrocal DA, Vishwanatha TM, Horn‐Ghetko D, Botsch JJ, Hehl LA, Kostrhon S, Misra M, Ðikić I, Geurink PP, van Dam H, Schulman BA and Mulder MPC (2023) A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity. Angew Chemie Int Ed, doi: 10.1002/anie.202303319 Link
González A, Covarrubias-Pinto A, Bhaskara R, Glogger M, Kuncha S, Xavier A, Seemann E, Misra M, Hoffmann M, Bräuning B, Balakrishnan A, Qualmann B, Dötsch V, Schulman B, Kessels M, Hubner C, Heilemann M, Hummer G and Dikic I (2023) Ubiquitination regulates ER-phagy and remodelling of the endoplasmic reticulum. Nature, doi: 10.1038/s41586-023-06089-2 Link
Foronda H, Fu Y, Covarrubias-Pinto A, Bocker HT, González A, Seemann E, Franzka P, Bock A, Bhaskara RM, Liebmann L, Hoffmann ME, Katona I, Koch N, Weis J, Kurth I, Gleeson JG, Reggiori F, Hummer G, Kessels MM, Qualmann B, Mari M, Dikić I and Hübner CA (2023) Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.Nature, doi: 10.1038/s41586-023-06090-9 Link
Lamond AI, Dikic I, Nussenzweig A, Müller CW, Thornton JM and Yaffe MB (2023) The mission to ensure continued funding for excellent basic research. EMBO Rep, doi: 10.15252/embr.202357498 Link
Bhattacharya A, Mukherjee R, Kuncha SK, Brunstein ME, Rathore R, Junek S, Münch C and Dikic I (2023) A lysosome membrane regeneration pathway depends on TBC1D15 and autophagic lysosomal reformation proteins. Nat Cell Biol, doi: 10.1038/s41556-023-01125-9 Link
Karantanou C, Minciacchi VR, Kumar R, Zanetti C, Bravo J, Pereira RS, Tascher G, Tertel T, Covarrubias-Pinto A, Bankov K, Pfeffermann L-M, Bonig H, Divieti-Pajevic P, McEwan DG, Giebel B, Münch C, Dikic I and Krause DS (2023) Impact of mesenchymal stromal cell–derived vesicular cargo on B-cell acute lymphoblastic leukemia progression. Blood Adv, doi: 10.1182/bloodadvances.2022007528 Link
Dikic I and Schulman BA (2023) An expanded lexicon for the ubiquitin code. Nat Rev Mol Cell Biol, doi: 10.1038/s41580-022-00543-1 Link
2022
Krause DS and Dikic I (2022) Mycobacterium tuberculosis hijacks ubiquitin to inhibit pyroptosis. Mol Cell, doi: 10.1016/j.molcel.2022.11.020 Link
Hertel A, Alves LM, Dutz H, Tascher G, Bonn F, Kaulich M, Dikic I, Eimer S, Steinberg F and Bremm A (2022) USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction. Cell Rep, doi: 10.1016/j.celrep.2022.111653 Link
Merline R, Rödig H, Zeng-Brouwers J, Poluzzi C, Tascher G, Michaelis J, Lopez-Mosqueda J, Rhiner A, Huber LS, Diehl V, Dikic I, Kögel D, Münch C, Wygrecka M and Schaefer L (2022) A20 binding and inhibitor of nuclear factor kappa B (NF-κB)-1 (ABIN-1) - a novel modulator of mitochondrial autophagy. Am J Physiol Physiol, doi: 10.1152/ajpcell.00493.2022 Link
Oo JA, Pálfi K, Warwick T, Wittig I, Prieto-Garcia C, Matkovic V, Tomašković I, Boos F, Izquierdo Ponce J, Teichmann T, Petriukov K, Haydar S, Maegdefessel L, Wu Z, Pham MD, Krishnan J, Baker AH, Günther S, Ulrich HD, Dikic I, Leisegang MS and Brandes RP (2022) Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell Rep, doi: 10.1016/j.celrep.2022.111670 Link
Voorneveld J, Kloet MS, Wijngaarden S, Kim RQ, Moutsiopoulou A, Verdegaal M, Misra M, Đikić I, van der Marel GA, Overkleeft HS, Filippov D V. and van der Heden van Noort GJ (2022) Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins. J Am Chem Soc, doi: 10.1021/jacs.2c06249 Link
Shah VJ and Đikić I (2022) Localization matters in targeted protein degradation. Cell Chem Biol, doi: 10.1016/j.chembiol.2022.09.006 Link
Karantanou C, Minciacchi VR, Kumar R, Zanetti C, Bravo J, S. Pereira R, Tascher G, Tertel T, Covarrubias-Pinto A, Bankov K, Pfeffermann L-M, Bonig H, Divieti-Pajevic P, McEwan DG, Giebel B, Münch C, Dikic I and Krause DS (2022) Impact of mesenchymal stromal cell-derived vesicular cargo on B-cell acute lymphoblastic leukemia progression. Blood Adv, doi: 10.1182/bloodadvances.2022007528 Link
Amstein LK, Ackermann J, Hannig J, Đikić I, Fulda S and Koch I (2022) Mathematical modeling of the molecular switch of TNFR1-mediated signaling pathways applying Petri net formalism and in silico knockout analysis. PLOS Comput Biol, doi: 10.1371/journal.pcbi.1010383 Link
Tiku V, Kew C, Kofoed EM, Peng Y, Dikic I and Tan M-W (2022) Acinetobacter baumannii Secretes a Bioactive Lipid That Triggers Inflammatory Signaling and Cell Death. Front Microbiol, doi: 10.3389/fmicb.2022.870101 Link
Gubas A and Dikic I (2022) ER remodeling via ER-phagy. Mol Cell, doi: 10.1016/j.molcel.2022.02.018 Link
Prieto‐Garcia C, Hartmann O, Reissland M, Braun F, Bozkurt S, Pahor N, Fuss C, Schirbel A, Schülein‐Völk C, Buchberger A, Calzado Canale MA, Rosenfeldt M, Dikic I, Münch C and Diefenbacher ME (2022) USP28 enables oncogenic transformation of respiratory cells and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.Mol Oncol, dio: 10.1002/1878-0261.13217 Link
Tomaskovic I, Gonzalez A and Dikic I (2022) Ubiquitin and Legionella: From bench to bedside. Semin Cell Dev Biol, doi: 10.1016/j.semcdb.2022.02.008 LinkTomaskovic I, Gonzalez A and Dikic I (2022) Ubiquitin and Legionella: From bench to bedside. Semin Cell Dev Biol, doi: 10.1016/j.semcdb.2022.02.008 Link
Cable J, Weber‐Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J, Jakob U, David DC, Bennett EJ, Bertozzi CR, Sardana R, Eapen V V. and Carra S (2022) Targeted protein degradation: from small molecules to complex organelles—a Keystone Symposia report. Ann N Y Acad Sci, doi: 10.1111/nyas.14745 Link
2021
Zhou J, Dabiri Y, Gama-Brambila RA, Ghafoory S, Altinbay M, Mehrabi A, Golriz M, Blagojevic B, Reuter S, Han K, Seidel A, Đikić I, Wölfl S and Cheng X (2022) pVHL-mediated SMAD3 degradation suppresses TGF-β signaling. J Cell Biol, doi: 10.1083/jcb.202012097 Link
Prieto-Garcia C, Hartmann O, Reissland M, Fischer T, Maier CR, Rosenfeldt M, Schülein-Völk C, Klann K, Kalb R, Dikic I, Münch C and Diefenbacher ME (2021) Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway. Cell Death Differ, doi: 10.1038/s41418-021-00875-z Link
Schünke H, Göbel U, Dikic I and Pasparakis M (2021) OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice. Nat Commun, doi: 10.1038/s41467-021-25945-1 Link
Prieto-Garcia C, Tomašković I, Shah VJ, Dikic I and Diefenbacher M (2021) USP28: Oncogene or Tumor Suppressor? A Unifying Paradigm for Squamous Cell Carcinoma. Cells, doi: 10.3390/cells10102652 Link
Mukherjee R, Bhattacharya A, Bojkova D, Mehdipour AR, Shin D, Khan KS, Hei-Yin Cheung H, Wong K-B, Ng W-L, Cinatl J, Geurink PP, van der Heden van Noort GJ, Rajalingam K, Ciesek S, Hummer G and Dikic I (2021) Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection. J Biol Chem, doi: 10.1016/j.jbc.2021.100925 Link
Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo‐San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen E, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T, Juhász G, Karantza V, Kraft C, Kroemer G, Ktistakis NT, Kumar S, Lopez‐Otin C, Macleod KF, Madeo F, Martinez J, Meléndez A, Mizushima N, Münz C, Penninger JM, Perera RM, Piacentini M, Reggiori F, Rubinsztein DC, Ryan KM, Sadoshima J, Santambrogio L, Scorrano L, Simon H, Simon AK, Simonsen A, Stolz A, Tavernarakis N, Tooze SA, Yoshimori T, Yuan J, Yue Z, Zhong Q, Galluzzi L and Pietrocola F (2021) Autophagy in major human diseases. EMBO J, doi: 10.15252/embj.2021108863 Link
Maculins T and Dikic I (2021) Gasdermin B in the host–pathogen tug-of-war. Cell Res, doi: 10.1038/s41422-021-00544-3 Link
Gerstmeier J, Possmayer A-L, Bozkurt S, Hoffmann ME, Dikic I, Herold-Mende C, Burger MC, Münch C, Kögel D and Linder B (2021) Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide. Cancers (Basel), doi: 10.3390/cancers13143577 Link
Valečka J, Camosseto V, McEwan DG, Terawaki S, Liu Z, Strock E, Almeida CR, Su B, Dikic I, Liang Y, Gatti E and Pierre P (2021) RUFY4 exists as two translationally regulated isoforms, that localize to the mitochondrion in activated macrophages. R Soc Open Sci, doi: 10.1098/rsos.202333 Link
Liu Y, Mukherjee R, Bonn F, Colby T, Matic I, Glogger M, Heilemann M and Dikic I (2021) Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection. Cell Death Differ, doi: 10.1038/s41418-021-00830-y Link
Armstrong LA, Lange SM, Dee Cesare V, Matthews SP, Nirujogi RS, Cole I, Hope A, Cunningham F, Toth R, Mukherjee R, Bojkova D, Gruber F, Gray D, Wyatt PG, Cinatl J, Dikic I, Davies P and Kulathu Y (2021) Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies. PLoS One, doi: 10.1371/journal.pone.0253364 Link
Schaefer L and Dikic I (2021) Autophagy: Instructions from the extracellular matrix. Matrix Biol, doi: 10.1016/j.matbio.2021.06.002 Link
Mukherjee R, Bhattacharya A, Bojkova D, Mehdipour AR, Shin D, Khan KS, Hei-Yin Cheung H, Wong K-B, Ng W, Cinatl J, Geurink PP, van der Heden van Noort GJ, Rajalingam K, Ciesek S, Hummer G and Dikic I (2021) Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection. J Biol Chem, doi: 10.1016/j.jbc.2021.100925 Link
Linder B, Klein C, Hoffmann ME, Bonn F, Dikic I and Kögel D (2021) BAG3 is a negative regulator of ciliogenesis in glioblastoma and triple‐negative breast cancer cells. J Cell Biochem, doi: 10.1002/jcb.30073 Link
Maculins T, Verschueren E, Hinkle T, Choi M, Chang P, Chalouni C, Rao S, Kwon Y, Lim J, Katakam AK, Kunz RC, Erickson BK, Huang T, Tsai T-H, Vitek O, Reichelt M, Senbabaoglu Y, Mckenzie B, Rohde JR, Dikic I, Kirkpatrick DS and Murthy A (2021) Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response. Elife, doi: 10.7554/eLife.62320 Link
Diehl V, Wegner M, Grumati P, Husnjak K, Schaubeck S, Gubas A, Shah VJ, Polat IH, Langschied F, Prieto-Garcia C, Müller K, Kalousi A, Ebersberger I, Brandts CH, Dikic I and Kaulich M (2021) Minimized combinatorial CRISPR screens identify genetic interactions in autophagy. Nucleic Acids Res, doi: 10.1093/nar/gkab309 Link
Hahn M, Covarrubias-Pinto A, Herhaus L, Satpathy S, Klann K, Boyle KB, Münch C, Rajalingam K, Randow F, Choudhary C and Dikic I (2021) SIK2 orchestrates actin-dependent host response upon Salmonella infection. Proc Natl Acad Sci, doi: 10.1073/pnas.2024144118 Link
Lo HS, Hui KPY, Lai H-M, He X, Khan KS, Kaur S, Huang J, Li Z, Chan AKN, Cheung HH-Y, Ng K-C, Ho JCW, Chen YW, Ma B, Cheung PM-H, Shin D, Wang K, Lee M-H, Selisko B, Eydoux C, Guillemot J-C, Canard B, Wu K-P, Liang P-H, Dikic I, Zuo Z, Chan FKL, Hui DSC, Mok VCT, Wong K-B, Mok CKP, Ko H, Aik WS, Chan MCW and Ng W-L (2021) Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir. ACS Cent Sci, doi: 10.1021/acscentsci.0c01186 Link
Kannt A and Đikić I (2021) Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation. Cell Chem Biol, doi: 10.1016/j.chembiol.2021.04.007 Link
Gubas A and Dikic I (2021) A Guide To… The Regulation Of Selective Autophagy Receptors. FEBS J, doi: 10.1111/febs.15824 Link
Klionsky DJ et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 8:1-382 Link
Gubas A, Karantanou C, Popovic D, Tascher G, Hoffmann ME, Platzek A, Dawe N, Dikic I, Krause DS and McEwan D. (2021) The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways. FEBS Lett, doi: 10.1002/1873-3468.14041 Link
Tiku V, Kofoed EM, Yan D, Kang J, Xu M, Reichelt M, Dikic I and Tan M-W (2021) Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii. Sci Rep, doi: 10.1038/s41598-020-79966-9 Link
Wells CI, Al-Ali H, Andrews DM, Asquith CRM, Axtman AD, Dikic I, Ebner D, Ettmayer P, Fischer C, Frederiksen M, Futrell RE, Gray NS, Hatch SB, Knapp S, Lücking U, Michaelides M, Mills CE, Müller S, Owen D, Picado A, Saikatendu KS, Schröder M, Stolz A, Tellechea M, Turunen BJ, Vilar S, Wang J, Zuercher WJ, Willson TM and Drewry DH (2021) The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. Int J Mol Sci, doi: 10.3390/ijms22020566 Link
2020
Shin D, Bhattacharya A, Cheng Y-L, Alonso MC, Mehdipour AR, van der Heden van Noort GJ, Ovaa H, Hummer G and Dikic I (2020) Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection. Elife, doi: 10.7554/eLife.58277 Link
van der Heden van Noort G, Kim RQ, Misra M, Alexis G, Tomašković I, Shin D, Schindelin H, Filippov D V., Ovaa H and Dikic I (2020) Development of ADPribosyl ubiquitin analogs to study enzymes involved in Legionella infection. Chem – A Eur J, doi: 10.1002/chem.202004590 Link
Waidmann O, Pleli T, Weigert A, Imelmann E, Kakoschky B, Schmithals C, Döring C, Frank M, Longerich T, Köberle V, Hansmann M-L, Brüne B, Zeuzem S, Piiper A and Dikic I (2020) Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis. Sci Rep, doi: 10.1038/s41598-020-73387-4 Link
CA, Conte I, Dikic I, Mann M, Ballabio A, Sacco F, Grumati P and Settembre C (2020) MiT/TFE factors control ER ‐phagy via transcriptional regulation of FAM134B. EMBO J, doi: 10.15252/embj.2020105696 Link
Maculins T, Garcia-Pardo J, Skenderovic A, Gebel J, Putyrski M, Vorobyov A, Busse P, Varga G, Kuzikov M, Zaliani A, Rahighi S, Schaeffer V, Parnham MJ, Sidhu SS, Ernst A, Dötsch V, Akutsu M and Dikic I (2020) Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chem Biol, doi: 10.1016/j.chembiol.2020.07.010 Link
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van der Heden van Noort GJ, Ovaa H, Müller S, Knobeloch K-P, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S and Dikic I (2020) Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature, doi: 10.1038/s41586-020-2601-5 Link
van der Heden van Noort G, Madern JM, Kim RQ, Misra M, Dikic I, Zhang Y, Ovaa H, Codee JDC and Filippov D V. (2020) Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitinating Enzyme SdeC. ChemBioChem, doi: 10.1002/cbic.202000230 Link
Putyrski M, Vakhrusheva O, Bonn F, Guntur S, Vorobyov A, Brandts C, Dikic I and Ernst A (2020) Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine. Front Cell Dev Biol, doi: 10.3389/fcell.2020.00208 Link
Tiku V, Tan M-W and Dikic I (2020) Mitochondrial Functions in Infection and Immunity.Trends Cell Biol, doi: 10.1016/j.tcb.2020.01.006 Link
Maddi K, Sam DK, Bonn F, Prgomet S, Tulowetzke E, Akutsu M, Lopez-Mosqueda J and Dikic I (2020) Wss1 Promotes Replication Stress Tolerance by Degrading Histones.Cell Rep, doi: 10.1016/j.celrep.2020.02.018 Link
Hübner CA and Dikic I (2020) ER-phagy and human diseases. Cell Death Differ, doi: 10.1038/s41418-019-0444-0 Link
Karathanasis C, Medler J, Fricke F, Smith S, Malkusch S, Widera D, Fulda S, Wajant H, van Wijk SJL, Dikic I and Heilemann M (2020) Single-molecule imaging reveals the oligomeric state of functional TNFa-induced plasma membrane TNFR1 clusters in cells.Sci Signal, doi: 10.1126/scisignal.aax5647 Link
2019
Pohl C and Dikic I (2019) Cellular quality control by the ubiquitin-proteasome system and autophagy.Science, doi: 10.1126/science.aax3769 Link
Herhaus L, Bhaskara RM, Lystad AH, Gestal-Mato U, Covarrubias-Pinto A, Bonn F, Simonsen A, Hummer G and Dikic I (2019) TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease. EMBO Rep, doi: 10.15252/embr.201948317 Link
Shin D, Mukherjee R, Liu Y, Gonzalez A, Bonn F, Liu Y, Rogov V V., Heinz M, Stolz A, Hummer G, Dötsch V, Luo Z-Q, Bhogaraju S and Dikic I (2019) Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB. Mol Cell, doi: 10.1016/j.molcel.2019.10.019 Link
Bhogaraju S, Bonn F, Mukherjee R, Adams M, Pfleiderer MM, Galej WP, Matkovic V, Lopez-Mosqueda J, Kalayil S, Shin D and Dikic I (2019) Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin-catalysed glutamylation. Nature, doi: 10.1038/s41586-019-1440-8Link
Forrester A, De Leonibus C, Grumati P, Fasana E, Piemontese M, Staiano L, Fregno I, Raimondi A, Marazza A, Bruno G, Iavazzo M, Intartaglia D, Seczynska M, van Anken E, Conte I, De Matteis MA, Dikic I, Molinari M and Settembre C (2019) A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex. EMBO J, doi: 10.15252/embj.201899847 Link
Huber J, Obata M, Gruber J, Akutsu M, Löhr F, Rogova N, Güntert P, Dikic I, Kirkin V, Komatsu M, Dötsch V and Rogov V V. (2019) An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5.Autophagy, doi: 10.1080/15548627.2019.1606637 Link
Linder B, Wehle A, Hehlgans S, Bonn F, Dikic I, Rödel F, Seifert V and Kögel D (2019) Arsenic Trioxide and (-)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling.Cancers (Basel), doi: 10.3390/cancers11030350 Link
Tiku V and Dikic I (2019) Autophagy without conjugation.Nat Struct Mol Biol, doi: 10.1038/s41594-019-0207-0 Link
Poluzzi C, Nastase MV, Zeng-Brouwers J, Roedig H, Hsieh LTH, Michaelis JB, Buhl EM, Rezende F, Manavski Y, Bleich A, Boor P, Brandes RP, Pfeilschifter J, Stelzer EHK, Münch C, Dikic I, Brandts C, Iozzo R V., Wygrecka M and Schaefer L (2019) Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury.Kidney Int, doi: 10.1016/j.kint.2018.10.037 Link
Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A and Kaulich M (2019) Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. Elife, doi: 10.7554/eLife.42549 Link
Bhaskara RM, Grumati P, Garcia-Pardo J, Kalayil S, Covarrubias-Pinto A, Chen W, Kudryashev M, Dikic I and Hummer G (2019) Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.Nat Commun, doi: 10.1038/s41467-019-10345-3 Link
Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I and Potente M (2019) Deubiquitinase USP10 regulates notch signaling in the endothelium. Science, doi: 10.1126/science.aat0778 Link
Nguyen D, Shaid S, Vakhrusheva O, Koschade SE, Klann K, Thölken M, Baker F, Zhang J, Oellerich T, Sürün D, Derlet A, Haberbosch I, Eimer S, Osiewacz HD, Behrends C, Münch C, Dikic I and Brandts CH (2019) Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy.Blood, doi: 10.1182/blood-2018-02-833475 Link
Herhaus L, van den Bedem H, Tang S, Maslennikov I, Wakatsuki S, Dikic I and Rahighi S (2019) Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains. J Mol Biol, doi: 10.1016/j.jmb.2019.06.012 Link
Mukherjee R and Dikic I (2019) NIPSNAP Beacons in Mitophagy. Dev Cell, doi: 10.1016/j.devcel.2019.05.008 Link
Juretschke T, Beli P and Dikic I (2019) Quantitative phosphoproteomics of selective autophagy receptors.Methods in Molecular Biology, doi: 10.1007/978-1-4939-8873-0_46 Link
van Wijk SJ, Fulda S, Dikic I and Heilemann M (2019) Visualizing ubiquitination in mammalian cells.EMBO Rep, doi: 10.15252/embr.201846520 Link